Fluoride Synergism Effects Leading To Rise In Worldwide Health Problems (Part 3)

Lucky discovery uncovers cancer-proof mouse By Shaoni Bhattacharya
 
A cancer-proof mouse, which can survive being injected with any number of cancer cells, has been discovered by US scientists. The discovery of the resistant mouse could pave the way for future gene or drug therapies if the mechanism by which it fights cancer can be understood
 
Researchers at the Wake Forest University School of Medicine in North Carolina have now bred a colony of 700 cancer-proof mice from the resistant male they stumbled across while doing other experiments.
 
Doctors have known for many years that in rare cases, cancers can mysteriously clear up of their own accord. But this is the first time such cancer-killing ability has been shown to be genetic.
 
“The power of this resistance seems to be unlimited,” said biochemist Zheng Cui, the study leader. “You can give them many, many tumour cells and the mice get rid of them.”
 
“This is at a preliminary stage, but very promising,” adds pathologist Mark Willingham, another member of the team. “Our hope is that, some day, this will have an impact on human cancer.”
 
Seven generations
 
The scientists discovered the original cancer-proof mouse by luck during experiments in which mice were injected with soft tissue cancers, called sarcomas. Despite repeated injections, one mouse did not develop cancer. When this mouse bred with a normal mouse, some of their offspring were resistant. And these resistant mice were also able to confer resistance, for at least seven generations. “The resistance appears to be caused by just one gene, or a cluster of closely related genes,” Cui told New Scientist.
 
The cancer-killing ability of the mice was unusually consistent with different types of cancer. “What’s surprising is it appears these mice are able to recognise something in common to all cancer cell lines,” said Cui. “Usually it’s difficult to find a common theme.”
 
Willingham told New Scientist that the cancer cells are killed by the mice in a “somewhat novel” way. The body’s usual first line of defence against invaders – white blood cells called T-cells – were not employed. Instead the body’s innate immune system, consisting of cells like neutrophils and macrophages, attacked the tumour cells and ruptured them.
 
Previous mice bred so that their immune systems could beat cancer went on the develop autoimmune diseases, but that did not happen with these mice. One significant puzzle that remains is how the mice detect the cancer cells in the first place. Cui speculates that some kind of diffusible factor from the tumour may betray the deadly cells.
 
Paul Ko Ferrigno, a cancer biologist at the MRC’s cancer cell research unit in Cambridge, UK, calls the findings “very tantalising”. “I’m intrigued and excited. If they can pin down what the immune basis for resistance to cancer is it should be straightforward to train a patient’s immune system to do the same,” he told New Scientist. Although they are preliminary, the study’s findings have “huge potential”, he says.
 
The top priority now, says Willingham, is to identify the mouse gene responsible for the resistance. “Because of the Human Genome Project, we could then look for a correlate gene in humans,” he said.

Fluoride Synergism Effects Leading To Rise In Worldwide Health Problems (Part 2)

The people of Russia and Europe have rejected the use of fluoridation because they know of its more sinister properties in taking control of societies. The Russian Jews that banned religions also likely saw through the real alchemical meanings from the veiled messages and parables presented in the Torah. Meanwhile, these communists stood by and watched the problems that wrecked Europe for so long be pilloried against the US and the UK. The toxic methods of fluoride have so lamed the minds of citizens of these countries that they don’t even notice the greater plan to take over the country from within, as forecast by Russia’s Khrushchev. Fluoride has some very sinister purposes once the Old World religion meanings are unveiled.
 
Fluorides released from industry causes problems and more sinister uses of fluorides to control people also cause problems. Natural effects are not exempted as even natural effects of fluoride levels are tied to the transmission of HIV and the resultant pandemic. The East African Rift Zone in Africa has the highest levels of HIV cases, and these areas also have the highest levels of fluoride in their food and water. Ref 2 below speaks to the issue of manganese being able to stop HIV reverse transcription replication and transmission in its tracks. This is one of the fluorine-metal complex effects that make for the problems of the HIV pandemic. The use of fluoride here is population control, and the Govt. does know the real issues behind HIV. It fits the Rockefeller depopulation plans.
 
In the human body the HIV virus tends to remain latent in the immune system cells of the abdomen, which is where the food and water intake would tend to affect the immune system the most. Other factors like gay male’s seamen also add to the concentration effects of fluorides because it tends to concentrate the fluoride toxics. Add to this that drugs like cocaine also affect the immune system and make HIV more infectious. This is how the gay population was so heavily affected by HIV.
 
The real issues of natural effects of fluoride and ever more sinister uses for it appear far back in history. Fluoride issues go back to the times of the origin of Alchemy in Egypt and the parable presentations in the Biblical narratives. The Egyptians were into religious rights used at mining temples to gather and purify gold. This was the source of the black chemistry called Alchemy. The Egyptians appear to be some of the first to observe that gold could be used as a medicine effect.
 
They did not know why at the time, only that it aided health. Today, we can see that gold added to the body tends to complex with fluorine and render it less harmful. This later went into how the Jews of Exodus survived the toxic effects of the Mt. Sinai volcano next to Midian. They added gold to their cooking methods as told by the golden calf story. Even today, the Chinese believe in adding gold flakes to their food and even cooking with a gold coin to achieve these same effect. We can see similar effects on the immune system and the susceptibility to flu be adding increased zinc to ones diet.
 
Moses was exposed to this mining temple Alchemy science linked to gold for the Egyptian royal courts. When Moses came for his people he used poison methods that were presented in alchemical imagery terms linked to symbols of the snake and the staff as power. Moses took his people to the Mt. Sinai volcano and here they did the mining techniques to extract gold from its deposits. They learned to survive the HF emissions by using the gold techniques. This is the heart of the science of colloid gold and silver, because these nano-fine particles gain entrance into the body and cells and can render the fluoride effect harmless by complexing with the fluorine atoms.
 
Even when get up to the times of Jesus we see the Egyptian Alchemy being involved linked to “Star Metals.” The only thing the Egyptians valued more than gold was the “Star Metal,” which was basically just low carbon iron from meteorites. It was the steel of the times, and highly valued. It was this substance that the Three Wise Men story of Jesus’ birth relates. The Jews wanted a new savior and the Wise Men liked the concept and imparted with them the inner secrets of the Alchemy.
 
Mary, Joseph, and thus Jesus learned the inner meanings of the story of Genesis and the methods of Moses and his volcano Alchemy from their contact with the alchemical wise men. They could then see through issues of the Jewish Torah in ways that had not been presented by Holy Rabbis of the times. Due to this inspirational epiphany of Mary and Joseph, Jesus became the reformer for the Jews over these inner secrets of the Torah (Torah is the first five chapters of Christian’s Bible). Even when we go back to Noah, we find the volcanic effects link to 40 days and nights of rain and the need to sequester food and shelter animals from the poisons of these events.
 
We can see these similar effects on animals today from volcanic events in Iceland, where the HF is cooled and deposited on the snows that melt and flow into rivers. The cattle and other animals hundreds of miles away from these events are often killed by drinking the HF contaminated water from the rivers. Similar effects are seen around aluminum plants where cows eat contaminated grass and either die or suffer extreme degenerative health effects.
 
Even the parable on Sodom and Gomorrah is one about the Dead Sea regions rift zone, which due to pressure and volcanic issues released all matter of fluorides into the ground water and wells of the region. What followed was toxic effects on the population there and the story that God or Nature destroyed them as it sank beneath the Dead Sea. This story is little different than the current problems in Ethiopia, where fluoride levels are extremely high in the water supplies and the rift effects are going to make in inland ocean of a large part of the country due to subsidence of the land.
 
We can even see the aphrodisiac effects of fluorides from the parables on Sodom and Gomorrah, and the very same effects happen to workers of the Govt.’s nuclear plants in Oak Ridge. These sex drive effects were so bad that all the office and lab windows and door glass had to be removed and replaced with clear glass to limit the private areas for sexual activities. Oak Ridge and other sites that experienced the toxic effects of fluorides got a unique visit back in time to the problems seen in the biblical narratives. It is how places like Oak Ridge unlocked the deeper issues of God and Nature from the Bible’s stories.
 
The secrets of religion are directly related to the alchemical science that evolved around the effects of fluorine from the Old World and the stories of the Old Testament. Jesus and the New Testament set forth to challenge the Torah and the Solomon’s Temple Jews or Pharisee that misinterpreted these alchemical images stories. Jesus held the greater sense on what was and was not God. The Old Testament is really the anti-Christ and the New is the Christ, and this is where the ultimate story of understanding the most electronegative element on the planet leads.
 
Those that truly understand the messages of Jesus would have to note that his message is about “Health Care” by prevention and not the “Illness Care” methods of today that have gone wild due to the suppression of toxic effects on the world population. Jesus was an Environmentalist of his times and he spoke against the deceptive war methods of Moses’ God using fluoride alchemical chemical warfare. This is the message shown in imagery by Mary standing on the Snake with an apple in its mouth to control the levels of poisons getting into the human food chain. It is the story of putting only good things into the body and treating it as a temple.
 
The science of fluorine is literally so pontifical that it is the divine gatekeeper between what are the concepts of Heaven and Hell for Humans on this planet. This is how powerful the study of the full issues of fluorine relates. Fluorine gets into the inner circle of the secrets of religion, and the flaws in the interpretations of religion. This is how fluorine comes to play such an instrumental role in the Revelations message of Jesus from the Biblical narratives.
 
Fluorine effects are directly linked to the great health plagues of cancer and HIV that we see today, as prophesied by Jesus in the Revelation narratives. The major weather effects are directly connected to the global warming effects being generated by fluorine building in the upper atmosphere. The full understanding of the effects of fluorine lead to the life-spans of 1,000 years presented in the Biblical Narratives Genesis. This being the best interpretation for “Eternal Life” and the saving messages from Jesus.
 
The Manhattan Project has played a pivotal role in the keeping of these huge secrets that have falsely empowered and mislead so many. It is linked to the messages of the End-Times, when false prophets have surrounded us. The Manhattan Project likes to falsely play up that radiation is the cause of the many health problems, but this is only an intentional misleading story salted into the public’s mind. The Manhattan Project and religion have long been linked in a mutual act of preservation of huge lies that are harmful to all citizens of this planet.
 
If the church gives up its inner sanctum secrets liked to these effects or the Manhattan Project scientists tell the real relationships, then both sides go down in a huge implosion. The Pharisee and those that followed them have tried to modify these simple origins of Moses God using much words of spirituality. But the inner core of Moses is one of the natural order of volcanic effects and this has both a warlike vengeful God connotation as well as one of Satan. These cover-ups are the root of all the massive wars the people of this world have been drawn.
 
The ultimate antithesis is fluoride sets up the ultimate contrast between reasons for communism’s ban on religion and those that pillory people with religion for power and control. Lost between the paradigms is the factor of good and the real God. The real dialectics Jesus spoke of are missing. The fact is that in the US, the war on communism used the church. The catharsis that exposes all is the study of fluoride connections to Egypt, the biblical narratives of Moses, and Jesus objections toward these spiritual words that attempted to conceal the real story. It is a story that most of the Jews that know Torah and Talmud know well.
 
It gets down to a method for the NWO, where the God of Moses is slipped into the bible narratives and not explained well to the Christian masses. It is explained so poorly that most think the God of Moses, the nationalistic God of the Jews, and the God of Jesus are one in the same. It is this omission and the conspiracy of silence tied to it, that is part of the Jews thinking their subtle take over methods are acceptable to organized religion in the US and the world. The war on communism has been used by the power seeking methods of the Jews to take control of the US.
 
It is ultimately the evangelical uses of spirituality to embellish these issues in such a way as to confuse and obfuscate them. It is done because these evangelicals are more interested in loosing a little money from the pocketbooks of their parishioners, more-so than telling the full story of correct spiritually and incorrect conspiracies of silence of the whole story. The real story is the church, as an ultimate weapon against communism and a tool for the Jews conquest, has presented a lie and a conspiracy of silence.
 
These are the methods of power and control using the false concepts presented by those of religion. This is the story of how science met religion in the Manhattan Project and beyond—and how the real message of Jesus was introduced to most in the US National Security system. Many of the very same interests that covered up the dangers of fluoride were the same players that cover up the reasons JFK was assassinated. It is the strong overlap of fluoride-related issues into Jewish / Torah religion factors and how these influenced the church and the war on Communism that played the essential role in the death of JFK. This is why Oak Ridge’s Y-12 plant played a preeminent role in the assassination of JFK by networking with Jacob Rubenstein, AKA Jack Ruby.
 
The war against communism is a no win when the best defenses are based upon a lie, and likewise a democracy built upon the false concepts of religion is doomed to be taken from within, a people exploited. Likewise, the church cannot be called a Church based in Christ, unless these truths become known. The Church has become a part of the Conspiracy of Silence that leads the flock astray. The only way to proceed now is all the facts on the table, the end of the secrecy, and return to the concepts of equality to all the people.
 
I hope that each of you have enjoyed these insights into the inner secrets of the Manhattan Project and the health effects of fluorides. May these secrets unleashed here set all free to enter a kinder and gentler time.
 

Fluoride Synergism Effects Leading To Rise In Worldwide Health Problems (Part 1)

Fluoride Synergism Effects Leading To Rise In Worldwide Health Problems
Original article by J. Phelps

This monologue is presented to orient persons, using plain language, to the problems associated with fluorine and fluoride chemicals.
 
If I were to name one element or one chemical compound that would represent the “Bane of Mans existence on Earth” it would be fluorine or fluoride. Fluorine has caused huge problems for man since the beginning of time due to volcanic effects on Earth. Fluorine or Hydrogen Fluoride released from volcanic events or even meteor terminal events is the principle effect for extinction events on this planet.
 
Fluoride in the body rises constantly with age and there is even one excellent book named for this effect: “Fluoride The Aging Factor” by Dr. John Yiamouyiannis [ISBN 0-913571-03-2]. Fluoride increases in the bones with age and all the effects of aging leading to immune system dysfunction and death track the retention of fluoride in the human body. Yianouyiannis and others have picked up on this effect. See excerpts of his book: Click Here and Here.
 
The industrial age has brought on a huge rise in the levels of fluoride in the air, water, and food supplies. Persons like German doctor Waldbott were some of the first to begin to point out the problems of fluoride. One of his books even presents the issue as the Dilemma: “Fluoride The Great Dilemma” by George Waldbott, MD [ISBN 0-87291-097-0] with foreword by Alton Ochsner, MD. Waldbott has this book foreword’d by one of the lead persons on the kill Castro with Cancer methods using SV-40 effects with a trigger of radiation or fluoride. See book excerpts: Waldbott Book.
 
More recent books speak to the huge cover up of industry and the US Govt. on the issues of fluoride connected to the nuclear bomb and strategic metals processing, see: “The Fluoride Deception” by Christopher Bryson [ISBN 1-58322-526-9]. Book Review. The health damages due to fluoride releases of these operations were so destructive that the Govt. with industry partners [DuPont, ALCOA, Rockefellers, Kettering Labs of Cincinatti, Oh.] decided to conceal the effects from the public. Kettering Labs is located where the occupation illness center in the US is located and Kettering is funded by the polluters and most all their files on fluoride research are kept locked away from the public. This has lead to extreme levels of abuse toward citizens and their health in the name of attempting to defeat communism. See: Kettering History.
 
Fluoride has been used as a pesticide for centuries and when looks for the method of which it kills bugs one quickly discovers the mechanism involves the upsetting of trace metal metabolism within cells. In insecticide uses, higher concentrations are applied, but when these same poisons enter the human food chain these same effects happen, only more slowly. Every human on the face of planet Earth is affected by this fluoride effect, some more that others depending on geographic, food consumption, industry, and water pollution. Fluoride is cumulative from even the subtlest levels taken in by human consumption.
 
The key to understanding the most damaging effect of fluoride is to know about these trace metal upsets that control enzyme repairs and other processes within cells. Upsets in these trace metals occur due to the fact that fluorine is the most electronegative element and when present within the body will cease onto trace metals spontaneously. This effect keeps these trace metals from being able to do their essential uses with the body and cells. This effect leads to rise in cell damages, higher levels of oxidation like damage to DNA, rises in the cytokine levels, loss of immune system tolerance in detection and elimination of varied pathogens, etc.
 
The problems associated with fluoride don’t stop with the metals-complex issues, as fluoride damage thyroid hormone due to iodine like valence effects, it damages the pineal gland and the melatonin / serotonin hormones, it contributes to arterial plaque, it upsets many of the immune cells like macrophage energy, it associates to heart attacks, kidney damage, and etc. If there were one element that was associated with the God of the Underground, Death, and Hell; it would be fluorine.
 
Fluoride effects are directly related to loss of IQ in children and the dumbing down of the population that makes them easier to lead. Fluoride effects linked to aluminum are linked to the passage of aluminum across the blood-brain-barrier that is linked with Alzheimer’s effects. Fluorides complex with aluminum to form G-protein like substances that are able to permanently upset cell bonding sites. Fluorides increase the retention of toxic metals in the body and lower the retention of beneficial trace metals, and this is a death keel to essential enzyme processes.
 
Fluorine was a large factor in the health problems in London due to the “London Fogs” that stemmed from the burning of high fluoride “Sea Coal.” These emissions produced fogs so thick they were called “Pea Soup” and persons had to lead carriages around the streets in broad daylight with lanterns. It is this same area that spawned the problems connected to Jack the Ripper, who appeared to be looking at the health effects of prostitutes connected to these toxic effects. A good book that goes into some of this is: “When Smoke Runs Like Water” by Dr. Devra Davis [ISBN 0-465-01521-1]. See excerpts: Here.
 
Fluorine began being exposed industrially in the 1930s in the Meuse Valley in Belgium from the emissions of aluminum processes, where it is used as a flux and melting point modifier for aluminum smelting. In the US in 1948, fluoride became a huge issue for the Donora, Pa. air inversion that trapped coal smoke and fluoride vapors from the flux operations of the steel mills there.
 
In the 40s era Manhattan Project it was a huge problem connected to national security and huge accidents near Buffalo, NY were concealed and problems from DuPont’s Peach Bottoms emissions were the start of huge Govt. sponsored cover ups on the damaging effects of fluorine processes. Fluorine was the only element that led to the lowest temperature gaseous form of uranium compounds.
 
One can see there formed a Govt. and industry sponsored cover up of the dangers of fluoride that matured into something to make it associated with good for children’s teeth. The truth of this deceptive process is that it put a deadly poison within the reach of nearly every child in America. The deadly truth is there is enough fluoride in one tube of the sweet and flavored toothpaste to kill an adult. Short of doses that kill the fluorides toxic effect robs children of their IQ, robs them of essential trace metals needed to immune health, and leaves them with a lifelong predisposition toward cancers, immune illnesses, and HIV.
 
When one knows and recognizes the issues of fluorine intake affecting the immune system, then other factors come into view. For example, rodents have long been associated with spreading the Black Plague bacteria in Europe. Most of these outbreaks have occurred correlated with major volcanic events. Rodents like to chew on bones to sharpen their teeth and this also puts high levels of fluorine into their diets. These levels tend to rise after volcanic events and this is associated to the immunity being damaged to the extent that the black plague bacteria are not controlled.
 
Since rodents have naturally been exposed to much higher levels of fluoride in their food chain due to the bone consumption, this effect has also upset the data derived from their use in medical research. Reference 1 below speaks to the finding of rodents by Wake Forest University with drastically different immune responses to cancer that all previous line of mice used in cancer research. The long isolation of mouse lines in captivity and their being fed low fluoride diets have lead to some of them recovering their immune functions. This basically means that all the data collected with mice has been flawed by the generational damage done by fluoride.
 
Bone meal fluoride is a huge undisclosed problem. It shows up in cattle fed bone meal leading to the issues of Mad-Cow or BSE. It shows up in gardeners who use bone meal on food they consume who then come down with similar illnesses. And it has shown up in children fed “pablum,” which was made from bone meal.
 
Natural fluoride effects even upset the reproduction of salmon fish, which must migrate into fresh water with less than the 1ppm fluoride in sea water. Various fish hatcheries have been harmed by fluoride levels of only 0.5 ppm in varied industrial cases.
 
Fluoride taken into the stomach is converted by the stomach acid to hydrofluoric acid, which is highly absorbed into the body and highly retained. It is a cumulative effect. The effect is most pronounced in rodents that consume bones that highly concentrate fluorine from the environment. The effect highly drives cancer resistance. This effect entered the studies on cancer as a weapon against Castro using SV-40 mutations.
 
DuPont’s mess made from fluorine not only made an ecological disaster from the Manhattan Project, it went on to wreck the world and even individual children’s young lives. DuPont made the lead for leaded gasoline. DuPont made the fluorine to make the UF-6 used to make the bomb uranium and they made the Teflon used to seal the processes and the Freon used to remove the heat of compression from the gas diffusion process. The Freon would go on to wreck the global environment due to the Fluorine being so close in mass to air that it lingers and builds in the upper atmosphere. Here it absorbs high levels of IR radiation and contributes to global warming and also sequesters hydrogen that adds to the UV-b levels from ionization effects.
 
The DuPont mess does not end there as the stain resistant compounds like “Scotchguard” is tied to Infant Deaths. Infants tend to burp up stomach contents and this gets onto Scotchguard surfaces of baby mattresses. Here the acid liberates the fluoride used in the stain resistant coating and makes HF, which can cause SIDS. Scotchguard has recently been discontinued due to these effects, in the same way that Freon has been discontinued. DuPont’s Teflon was even seen to break down in cooking applications and poison and kill household birds.
 
The Manhattan Project is riddled with fluorine problems. The very first deaths connected with the project came from liquid diffusion experiments hitting some water causing a huge explosion and HF release that killed several people. The problems never ceased, as in Oak Ridge they killed a worker named Jack Owens who sat on some “Green Salt” at the Y-12 plant that was wet with HF and he died of a heart attack a few days later. HF has a sudden death effect due to skin absorption effects on the heart. Persons like Paducah’s Joe Harding cleaned out gas diffusion equipment and received HF exposures by crawling around and getting HF into his tendons around knees, elbows, etc. The fluoride hardened his ligaments and these would flake off and look like fingernails coming through his skin. He eventually died of stomach cancer.
 
Fluoride even has some more sinister uses, as it was used in Russia and in Germany to pacify prisoners. The infamous “Red Trains” of Russia took undesirables to work camps in Siberia. Here the Jewish operators of these camps administered the fluoride to change resistant attitudes. Ironically, Jewish Communist in Russia banned religions due to some of the problems of state within a state effect that religion caused that challenged the power of Governments. Many of these religious dissidents landed in these Jewish operated Siberian prisons and were given the same methods of treatment that Moses dealt to the Egyptians using the alchemical methods of fluoride.
 

What is Hyaluronic Acid?

Hyaluronic Acid (also called Hyaluronan and Hyaluronate) is a non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is one of the chief components of the extracellular matrix, contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumours. The average 70-kg man has roughly 15 grams of Hyaluronic Acid in his body, one-third of which is turned over (degraded and synthesised) every day.

Until the late 1970s, Hyaluronic Acid was described as a “goo” molecule, a ubiquitous carbohydrate polymer that is part of the extracellular matrix. For example, Hyaluronic Acid is a major component of the synovial fluid and was found to increase the viscosity of the fluid. Along with lubricin, it is one of the fluid’s main lubricating components.

Hyaluronic Acid is an important component of articular cartilage, where it is present as a coat around each cell (chondrocyte). When aggrecan monomers bind to Hyaluronic Acid in the presence of link protein, large highly negatively-charged aggregates form. These aggregates imbibe water and are responsible for the resilience of cartilage (its resistance to compression). The molecular weight (size) of Hyaluronic Acid in cartilage decreases with age, but the amount increases.

Hyaluronic Acid is also a major component of skin, where it is involved in tissue repair. When skin is excessively exposed to UVB rays, it becomes inflamed (sunburn) and the cells in the dermis stop producing as much Hyaluronic Acid, and increase the rate of its degradation. Hyaluronic Acid degradation products also accumulate in the skin after UV exposure.

While it is abundant in extracellular matrices, Hyaluronic Acid also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions, notably those including its primary receptor, CD44. Upregulation of CD44 itself is widely accepted as a marker of cell activation in lymphocytes. Hyaluronic Acid’s contribution to tumour growth may be due to its interaction with CD44. Receptor CD44 participates in cell adhesion interactions required by tumour cells.

Although Hyaluronic Acid binds to receptor CD44, there is evidence that Hyaluronic Acid degradation products transduce their inflammatory signal through Toll-like receptor 2 (TLR2), TLR4 or both TLR2, and TLR4 in macrophages and dendritic cells. TLR and Hyaluronic Acid play a role in innate immunity.

High concentrations of Hyaluronic Acid in the brains of young rats, and reduced concentrations in the brains of adult rats suggest that Hyaluronic Acid plays an important role in brain development.

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DMSO: A New Approach to Rheumatic Diseases

DMSO: A New Approach to Rheumatic Diseases

No matter how many non-steroidal anti-inflammatory, immuno-suppressive, and cortisone-related drugs were introduced in the past year as first option for rheumatic diseases, the improvement obtained was poor because most of the time we only control the pain and the inflammatory symptoms, but the disease continues to destroy the tissues.

Because of this situation, four years ago we proposed a triple approach for sero-negative and sero-positive rheumatic diseases with clinical and laboratory results above what we originally expected.

The triple approach includes:

1. DMSO (Dimethylsulfoxide) one of the most powerful antioxidants known, and has a strong anti-inflammatory effect. It has been used since 1940 as an industrial solvent, and after the studies of Jacobs was included in 1960, for osteo-muscular diseases.

In 1978 the FDA approved the use of DMSO for interstitial cystitis, but there are multiple studies showing an improvement in different pathologies with the use of DMSO.

In degenerative diseases like Osteoarthritis free radicals (FR) attach and degenerate the cartilage, decreasing the space in between the bones of the joint, and this contact will produce pain with movement.

In inflammatory diseases, FR are closely related to leukotrines synthesis as described in pathologies like rheumatic arthritis. In both cases DMSO will decrease the synthesis of FR, inhibiting its deleterious effect on the bone structures.

Experimental studies in animals confirmed that DMSO dissolves the collagen of the fundamental matrix, improving elastic tissue and increasing the elimination of hydroxyproline, only in patients with collagenopathies, but not in normal individuals.

2. Enzymo-Injection-Pressure (EIP) consists in using a complex formula in order to create pressure points in the ailing joints; this approach has anti-pain, anti-inflammatory and fibrinolitic effects.

It works by a pressure mechanism that will stimulate the amyelinated fibres that measure from 5 to 15 microns in diameter, and send to the brain the pressure stimuli with a speed of 30 to100 meters per second. By this method the pressure stimuli will always arrive first at the brain regulatory centre over the pain stimuli.

The formula (called F3) included in each 30cc multiple vial dose the following:

- papain 0.005 grams
- hyaluronidase 0.001grams
- trypsin 0.005 grams
- UTP 0.001 grams
- novocaine chloride 0.100 grams
- saline solution 0.9% 30 cc

3. Mucopolysaccharides, also called glycoaminoglycans, formed by the hyaluronic acid, chondroitan and dermatan sulphate, that are components of the fundamental matrix, and are used to stimulate the mitotic activity of the condrocytes to keep the cartilage integrity.

After a follow-up of three years in 36 eligible patients with Osteoarthritis, we prepared a retrospective analysis that soon will be published, where we obtained the following results:

a. From the 36 patients included in the follow up, 33 (91.66%) had a complete recovery of the general signs and symptoms as: joint swelling, joint pain, limitation of movements, morning rigidity, crippling, partial social inactivity.

The other 3 (8.45%) had a partial recovery but much better than obtained with traditional therapy, and without side effects.

b. The important aspect of thus study was that it included only patients that had been using three or more different kinds of anti-rheumatic drugs as follows:

- 100% use nonsteroidal drugs
- 89% use or used cortisone
- 66.6% use or used oral gold salts
- 22.7% use or used IM gold salts
- 18% use or used different kinds of immunosuppressive drugs
- 0% plasmapheresis

c. Thirty two (89%) of the patients were women and 4 (11%) men. Our protocol included an intensive course of treatments for 5 weeks and a maintenance therapy monthly.

d. Nine patients (25%) had a partial recurrence.

e. Multiple joint diseases were included: coxo-femoral, knee, shoulder, hand (interphalangeal distal) cervical and lumbar backbone, etc.

In the last two years we included patients with Rheumatoid Arthritis and sero-negative rheumatic diseases. After more than 500 patients were treated we are extremely positive of this triple approach for rheumatic disease and we present the following conclusions:

1. The triple approach therapy is highly successful in patients with Rheumatoid Arthritis but it takes more treatments in the first part of the therapy; however in our opinion this therapy modality keeps the patients antisymptomatic for longer periods of time.

2. Patients with Ankylosing Spondylitis represent a small number of our patients, but the improvement seen in these patients is sometimes astonishing compared to the usual approach (anti-inflammatories and physiotherapy).

3. Other sero-negative rheumatic patients have variable results that suggest more intensive studies in each particular disease.

4. Finally, patients with Rheumatoid Arthritis and Psoriasis, Lupus Erythematosis and other autoimmune diseases complicated with joint pathology need more attention, but it seems that we can get an outstanding therapeutic result in a long-term therapy. But we still need longer follow-up studies in these specific diseases.

As we know, one third of the population over 35 suffer from Osteoarthritis and millions of others suffer from Rheumatoid Arthritis and other rheumatic diseases, so we should consider this group of pathologies the most crippling diseases in the world.

Most of the drugs used for rheumatic disease are associated with heavy side effects, a situation not observed with the triple approach therapy.

Conclusions

Rheumatic diseases represent one of the most crippling of all diseases and deserves special attention because most of the control is done by drugs associated with side effects, which only control pain and inflammation no matter how fast the disease develops.

Simultaneously using DMSO plus Mucopolysaccharides and enzymo-pressure-injection, seems to be an important way to control the disease evolution, and at the same time, gets the patient back to normal activities. In this kind of therapy we did not find any complications and no side effects. Instead we find extremely important improvements in the patients treated.

As much as we know of the implication of the free radicals (FR) with degenerative and inflammatory pathologies, more important seems to be the relationship with antioxidants like DMSO.

Regrowing damaged, but not dead cells is possible when we can offer the tissues that which is necessary material for autoregeneration. The homeostasis of the body is a result of the equilibrium between tissues. That is the mechanism of action of our triple conjugate therapy for rheumatic diseases.

Methods and Materials: Control of Free Radicals with DMSO

Thirty patients were included, 15 of them with RA, and 15 with OA, with a follow-up of 18 months.

The antioxidant used was DMSO (Dimethylsulfoxide in doses of 5 cc for each therapy together with B complex, Vitamin C, and Magnesium Sulphate) in a five-week, twice-weekly for the first period, and a follow-up of one bottle monthly for 18 months.

As we know DMSO3 is one of the most powerful antioxidants known, that also blocks the CH-(hydroxyl) FR (It is well known that the human body does not have any antioxidant enzyme to block its formation.)4. DMSO is also an important anti-inflammatory substance, and as we showed in another study, is extremely useful in patients with inflammatory and degenerative diseases.

In order to measure the FR production we used the method HLB (Heitan-La Garde-Bradford)5 that determines the presence of ROTS (reactive oxygen toxic species), mostly formed by FR, that plays a role in virtually all disease states and metabolic dysfunctions.

The production of ROTS affects the basic cellular structures and metabolic pathways and also reacts with blood constituents to form various by-products which can be seen as morphological changes in the blood. The specific morphological changes in the blood vary as a function of the pathological condition; in this case on Rheumatoid pathologies, strength of the immune system, specific ROTS as well as level of ROTS being generated.

The study includes the extracellular matrix formed by: proteoglycan (as chondroitin sulphate, dermatan sulphate), hyaluronic acid, collagen and elastin. Each of these substances may be degraded by enzymes specific to each substance. The degradation enzymes are as follows: chondrotinase (degrades condroitin sulphate), hyaluronidase (degrades hyaluronic acid), collagenase (degrades collagen) and elastase (degrades elastin).

In patients with Rheumatoid pathologies, we can find, as seen in induced-experimental arthritis studies in rats, the activity of collagenase increase in skin, bone, liver, kidney, and spleen, while that of hyaluronidase decreased significantly in liver, kidney and spleen6. When traumatised normal pig synovia was cultured with normal pig cartilage for 14 days the breakdown of cartilage collagen and proteoglycan was accompanied by the appearance of both collagenase and proteoglycanase7. Studies in patients with inflammatory Rheumatoid Arthritis indicated an increase of prolyl hydroxylase in 70% of those with active disease8.

The measuring of ROTS was done in the first visit of the patient to the office, a second measure was done after any one of the infusions of DMSO, and the third evaluation after 18 months in order to measure its antioxidant effect in long-term therapy in maintenance doses.

Results: In a recent study9,10 we showed that antioxidants are extremely important in order to control the synthesis of FR, as well as the symptoms of patients with Osteoarthritis. As we know FR are closely related to degeneration in OA, and also in the inflammatory response in patients with RA.

From the beginning we have used in patients with rheumatoid diseases the antioxidant DMSO (Dimethylsulfoxide) that has an important role over the OH-FR, instead of the popular antioxidant EDTA, that we use in patients with cardiovascular diseases as we show in our other studies11,12

Our protocol in the last 5 years includes: one infusion twice weekly for 5 weeks, followed by one weekly or each 15 days, followed by one infusion monthly for as long as 1 or 2 years. With this protocol we have been successful in over 85% of patients with OA, and over 77% in patients with RA, with long-lasting effects, without using any other oral or parenteral non-steroidal or steroidal anti-inflammatory.

The 30 patients included in this study were regular patients in our clinic and were evaluated three times in order to see if it was possible to use the HLB test as a measuring method of FR, as well as DMSO as an optimum antioxidant. The results obtained are represented in Figure 1, where we find an initial average FR measuring 30.6% of the patients included, with an important and significant decrease of FR production after DMSO administration, obtaining lower levels with an average of 10.6%. That represents a 66% decrease in patients before beginning the DMSO therapy, and keeping the patients in monthly applications we obtained an average of 13.3% of FR synthesis. That represents 52% decrease than the patients had in the beginning, and 12% higher than patients after any DMSO infusion.

It is important to verify that the higher values were obtained in patients with RA, and the lowest in patients with OA.

The Best in the World Use MSM: The National Stud

In July, 2010, we took a holiday to the UK to visit family, friends and relatives. During our stay in the UK, we also visited the National Stud in Newmarket.

And guess what we discovered after a little research… The top-quality food stuffs fed to the stallions (and we’re talking about Grand National Winners here), contains MSM. Stallions such as Bahamian Bounty, whose stud fee is $16,000, Cockney Rebel, Pastoral Pursuits and Phoenix Reach to name but a few, are all fed with the finest quality feed, containing MSM. We also encountered 2004 Grand National Winner; Amberleigh House, now retired and with a taste for Polo mints! He is also fed the same  MSM enriched feed.

So; if it’s good enough for the National Stud, worth millions of dollars, it’s got to be good enough for you, and your horse(s).

About the Stud
The National Stud is a United
Kingdom Thoroughbred horse breeding farm located three
kilometres from Newmarket. The Stud originated in 1916
as a result of a gift by William Hall Walker (later Lord
Wavertree) of the entire bloodstock of his stud farm in
Tully, Kildare town in County Kildare, Ireland. As part
of the arrangement, the British government acquired the
Irish property along with Walker’s training stables in
England. In 1943, the newly formed Irish Government took
over the Tully property and the Irish National Stud
Company Ltd. was formed. The Irish bloodstock was then
transferred to the Sandley Stud in Dorset. The stud’s
operations were expanded after the World War II with the
purchase of a stud at West Grinstead in Sussex.
.. Read more here.

DMSO – Control of Free Radicals in Rheumatoid Arthritis and Osteoarthritis

DMSO – Control of Free Radicals in Rheumatoid Arthritis and Osteoarthritis

Rheumatoid diseases are some of the most crippling pathologies on earth. Statistically one-third of individuals more than 35 years old suffer from Osteoarthritis, and also a large number of patients with Rheumatoid Arthritis, two of the most common diseases of this group of pathologies.

Rheumatoid Arthritis (RA) is an autoimmune disease, and Osteoarthritis (OA) is a degenerative disease, but both have something in common. They are closely related to Free Radical (FR) synthesis, as an inflammatory disease in RA in the prostaglandin metabolism and synthesis of leukotrienes, and in the destruction of cartilage in patients with OA2.

Considering that these two pathologies are the most frequently seen in rheumatoid diseases we decided to study a correlation between FR synthesis before therapy, attempting to measure the decrease of FR production using antioxidant therapy with the following objectives:

1. Confirming that there is a relationship between FR synthesis with both diseases;

2. If the antioxidant therapy works not only with clinical improvement but also with an important reduction in the FR production;

3. How we can keep, if possible, the low levels of FR in these patients — helping to keep the patient asymptomatic for long periods of time.

DMSO: Treatment of Arthritis

Several years ago Ronald M. Davis, M.D. demonstrated, in our publication A Treatment for Scleroderma & Lupus Erythematosus, the strategic use of DMSO (Dimethylsulfoxide). We’ve also reported on the good results of DMSO used with and without EDTA (Ethylene Diamine Tetracetic Acid) in our Chelation Therapy.

DMSO is a prolific and inexpensive by-product of the pulp paper industry. Its medical uses has been reported many times, by many people, but especially in the works of chemist Robert J. Herschler and surgeon Stanley Wallace Jacob, M.D., and also as popularised by Pat McGrady, Sr. in The Persecuted Drug: The Story of DMSO13.

The external and internal use of DMSO by veterinarians for pain in animals has long been accepted. Those humans who’ve managed to obtain a sufficiently pure variety of DMSO have also benefited from its pain-relieving qualities. Apparently, as Ronald M. Davis, M.D. has learned, when used in an IV over a number of months, even the most hopeless cases of Scleroderma and Lupus Erythematosus can be drastically reversed; while its use (as developed by Ray Evers, M.D. (deceased) in EDTA/DMSO IVs has long been accepted by many holistic physicians for peripheral circulation problems, as well as many other problems all of which are related — as is Scleroderma and Lupus Erythematosus — to free radical excess in the human physiological systems.

Those of us who’ve suffered from Rheumatoid Diseases of one or the other of the 75 to 100 differently named collagen tissue diseases know the nature of free radical pathology first hand. We could not, on the best of days, dispute that collagen tissue diseases (Rheumatoid Diseases) generate as a by-product many free radicals which create havoc with every working apparatus of our human bodies.

The message to be learned from the pioneer physicians Stanley Jacobs, Roger Wyburn-Mason, M.D., Ph.D., Dr. Paul K. Pybus, Jack Blount, M.D., Gus Prosch, Jr., M.D., Ray Evers, M.D., Ronald Davis, M.D., Efrain Olszewer, M.D., Fuad C. Sabbag, M.D., Alan Rory Zapata, M.D. and others is that (1) collagen tissue diseases can be licked; (2) the pain of these diseases do not need to be endured; (3) one does not need to destroy self with the use of cytotoxic drugs, gold, penicillamine or long-term corticosteroids to rid oneself of the disease and its effects. Indeed, we have now learned that all of these traditional rheumatic treatments generate more dangerous free-radicals than the disease itself, thus over-burdening the body even further.

It is clear in the reports that follow that Doctors Olszewer, Sabbag and Zapata, along with Jacobs, Evers and Davis, have added new and important knowledge to our persistent search for wellness.